A Study to Evaluate Neurostimulation to Treat Chronic Upper Limb Pain After Brachial Plexus Injury


About this study

This study is designed to assess the degree to which high-frequency spinal cord stimulation may help with pain after brachial plexus avulsion injury.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years old.
  • Neuropathic pain of the upper limb ≥ 3 months following brachial plexus avulsion injury.
  • Patients must be planned to undergo trial of high-frequency spinal cord stimulation for the treatment of chronic neuropathic pain due to brachial plexus avulsion injury.

Exclusion Criteria: 

  • Pregnant at the time of consideration for trial and/or implant per patient report.
  • Active substance use disorder of any kind.
  • Active tobacco use.
  • Use of moderate or high dose opioid medication (oral morphine equivalents >100 mg daily).
  • Active, untreated major psychiatric disorder that might interfere with subject’s ability to participate.
  • Involvement in active litigation related to injury per patient report.
  • Patient has not undergone conservative medical management for at least 3 months (including physical and/or occupational therapy and at least one trial of neuropathic pain medication).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Christine Hunt, D.O.

Open for enrollment

Contact information:

Christine Hunt D.O.

(507) 538-5510


Jacksonville, Fla.

Mayo Clinic principal investigator

Christine Hunt, D.O.

Open for enrollment

Contact information:

Clinical Studies Unit

(904) 953-2255

More information


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