Thymus Tissue Collection


About this study

Thymus tissue is standardly removed during neonatal congenital cardiac surgery. The collection of this tissue poses no additional risk to subjects. TRAG’s standard operating procedures will be followed to prepare, store, and provide the discarded tissue to Dr. Tuggle. An internal database will be used to record consent, date of collection, and date of shipment. After collection of the thymus tissue, there will be no further contact with subjects or families.  There will be no results to report and no information will become part of the subject’s medical record.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age 0 to 9 months at the time of surgery.
  • Undergoing a planned congenital cardiac surgery at Mayo Clinic.
  • All races, ethnicities, and sexes are eligible.

Exclusion Criteria:

  • Age 9 months or older at the time of surgery.
  • Patients undergoing a cardiac surgery that will not include the standard remove and disposal of thymus tissue.
  • Subjects whose parents/guardians are unwilling or unable to give consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Timothy Nelson, M.D., Ph.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Karen Miller CCRP

(507) 266-5510

More information


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