Determining the Effectiveness of the Sphenopalatine Ganglion (SPG) Block for the Treatment of the Postdural Puncture Headache

Overview

About this study

The purpose of this study is to analyze the effectiveness of the sphenopalatine ganglion (SPG) block with lidocaine vs. SPG block with placebo in preventing the need for epidural blood patch (EBP) in women who develop post dural puncture headache (PDPH) after accidental puncture during placement of lumbar epidural anesthesia (LEA) for labor.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Females, age 18-50;
Post dural puncture headache (PDPH) after documented accidental dural puncture during placement of lumbar epidural anesthesia (LEA);
No better explanation for headache;
Onset of headache within 72 hours of delivery.

Exclusion Criteria:

Patient refusal;
True allergy to local anesthesia;
Hereditary Hemorrhagic Telangiectasia;
Inability to understand pain scores and other questionnaires;
Inability to speak English;
Contraindication to acetaminophen or NSAIDs;
Temperature >38.5 C;
Prior epidural blood patch (EBP) done for this headache.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status
Rochester, Minn. Mayo Clinic principal investigator Emily Sharpe, M.D.	Closed for enrollment

Mayo Clinic Location

Status

Rochester, Minn.

Mayo Clinic principal investigator

Emily Sharpe, M.D.

Closed for enrollment

More information

Publications

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