A Study to Evaluate RNA Transcriptomics for Predicting Allograft Failure or Rejection


About this study

The primary purpose of this study is to evaluate the feasibility of analysis of RNA transcripts from EVs sampled from the coronary sinus.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Planned endomyocardial biopsy post-cardiac transplant.
  • Suitable anatomy for coronary sinus sampling and successful retrieval of coronary sinus blood.
  • Ability to provide informed consent and consent for the study.

Exclusion Criteria:

  • Multiorgan transplant aside from heart-kidney.
  • Refusal of study participation.
  • Unsuccessful endomyocardial biopsy.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Atta Behfar, M.D., Ph.D.

Open for enrollment

Contact information:

Erin Gillmore

(507) 422-6736


More information


Publications are currently not available

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