Detection of Vascular and Inflammatory Plasma Biomarkers in Patients Diagnosed with Obstructive Sleep Apnea and MRI-defined Cerebral Small Vessel Disease

Overview

About this study

The purpose of this study is to evaluate plasma biomarkers of vascular function and inflammation in patients with newly-diagnosed Obstructive Sleep Apnea (OSA) and pre-existing imaging evidence of Cerebral Small Vessel Disease (CSVD).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults ≥ 50 years of age.
  • Diagnosed with Obstructive Sleep Apnea (OSA) (AHI ≥ 5 per CMS criteria).
  • Ability to provide informed consent.
  • English as native language.

Exclusion Criteria:

  • Patients with a pre-existing ischemic or hemorrhagic stroke within the lat 90 days.
  • Enrollment in a randomized trial or registry of an experimental drug or device.

Eligibility last updated 9/3/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

James Meschia, M.D.

Open for enrollment

Contact information:

Melissa Rompola CCRP

(904) 953-4516

Rompola.Melissa@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20491455

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