A Study of Bowel Function Return After One or Two Level Anterior Lumbar Interbody Fusion with Chewing Gum


About this study

The purpose of this study is to observe changes in bowel pattern based on gum-chewing, examine bowel function after anterior lumbar interbody fusion, measure length of time to return of bowel function after anterior lumbar interbody fusion, compare return of bowel function in patients who chew gum and patients standardized to usual post-operative care, measure the hospital length of stay amongst study groups, and measure post-operative pain amongst study groups.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Undergoing one or two level anterior lumbar interbody fusion.
  • Diagnosis of spondylosis, spondylolisthesis, revision of foraminal stenosis or neurogenic claudication.

Exclusion Criteria: 

  • Previous bowel surgery.
  • Diagnosis of an inflammatory bowel disease.
  • Allergy to xylitol.
  • Pregnancy.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Maziyar Kalani, M.D.

Open for enrollment

Contact information:

JoDee Winter P.A.-C.


More information


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