A Study to Evaluate the Natural History of Barrett's Esophagus Using Tethered Capsule Endomicroscopy

Overview

About this study

The goal of this research is to determine the natural history of Barrett's esophagus (BE) using tethered capsule endomicroscopy (TCE) in patients undergoing surveillance endoscopy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with known Barrett’s Esophagus (BE) without high grade dysplasia, intramucosal adenocarcinoma or esophageal adenocarcinoma, confirmed by endoscopic biopsy.
  • Patients over the age of 18.
  • Patients who are capable of giving informed consent.
  • Patients who had or will have a standard of care EGD within 9 to 15 months.
  • Subjects must have no solid food for at least 4 hours prior to the procedure, and only clear liquids for 2 hours prior to the procedure.

Exclusion Criteria:

  • Patients with prior endoscopic ablation or resection treatment of BE.
  • Patients with esophageal fistula and/or esophageal strictures with a luminal stricture diameter that is smaller than the diameter of the capsule.
  • Patients with the inability to swallow capsules.
  • Pregnancy, according to patient information.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Michael Wallace, M.D.

Open for enrollment

Contact information:

Herbert Wolfsen M.D.

(904) 953-6970

Wolfsen.Herbert@mayo.edu

Rochester, Minn.

Mayo Clinic principal investigator

Kenneth Wang, M.D.

Open for enrollment

Contact information:

Bryan Linn

(507) 255-4631

Linn.Bryan@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20491413

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