Clinical Trials

Inclusion Criteria:

• Age >18 year.
• Suspected Suspected acute infection (respiratory, urinary, abdominal, skin & soft-tissue), and at least one of the symptoms; OR
• Suspected sepsis of any cause as defined by a blood culture order by the treating physician, and at least two of the symptoms:
  • Heart rate: > 90 beats/ minute;
  • Temperature: > 38C or < 36C;
  • Respiratory Rate: > 20 breaths / minutes or PaO2 of < 60 mmHg or SpO2 < 90%;
  • Systolic blood pressure: < 100 mmHg;
  • Altered mental status: Per clinical exam.
• Able to provide informed consent, or consent by legally authorized representative.

Exclusion Criteria:

• Patient-reported treatment with systemic antibiotics, systemic antiviral agents, or systemic antifungal agents within the past 7 days prior to the emergency department study visit. Participants will not be excluded for the following:
  • Use of topical antibiotics, topical antiviral or topical antifungal agents;
  • Use of peri-operative (prophylactic) antibiotics;
  • Use of a single dose of antibiotics during the present ED visit (< 6h before blood draw).
• Prisoners, mentally disabled, or unable to give consent. Should the patient not be able to provide informed consent the legally authorized representative can provide the consent on behalf of the patient..
• Previously enrolled in the present clinical trial.