A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis

Overview

About this study

The purpose of this study is to evaluate shear wave data and vascular lumen size determined by Contrast-Enhanced Ultrasound (CEUS) in patients undergoing temporal artery biopsy, to determine the sensitivity and specificity of Shear Wave Elastography (SWE) and CEUS for the diagnosis of temporal arteritis, and to determine the impact of pre-operative ultrasound guided mapping on operative time required for temporal artery biopsy.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adult male and non-pregnant women 18 years old or older.
  • Subject has suspected temporal arteritis.
  • Subject is scheduled for TAB based on clinical diagnostic protocol.
  • Subject is able to understand the study procedure and provide informed consent.

Exclusion Criteria:

  • Subject has an established prior diagnosis of temporal arteritis/giant cell arteritis.
  • Subject is pregnant or breast feeding.
  • Subject is unable to provide informed consent.
  • Subject has contraindication to the use of the Lumason contrast agent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Lilly Wagner, M.D.

Open for enrollment

Contact information:

Jessica Morgan C.O.A.

(507)293-9689

Nolte.Jessica@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20485249

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