A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy


About this study

The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Fuchs Endothelial Corneal Dystrophy (FECD): Presence of central or paracentral corneal guttae with or without corneal edema. (Controls will not have any guttae).
  • Any age (expected range will be 40-90 years).
  • Any sex or race.
  • Subjects who have previously undergone uncomplicated cataract surgery (to eliminate the confounding effect of cataract on vision) at least 2 months prior to enrollment.

Exclusion Criteria: 

  • Any ocular disease that is known to affect vision (e.g., cataract, macula/retinal disease, amblyopia, etc.).
  • Previous corneal transplantation in both eyes.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sanjay Patel, M.D.

Open for enrollment

Contact information:

Sanjay Patel M.D.



More information


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