A Study to Investigate the Molecular Foundation of Spinal Tissue


About this study

The purpose of this study is to identify molecular mechanisms that control the rate of disc-dehydration, the effect of degeneration on surrounding bone and ligaments, and identify agents that can be used to alter the course of the disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults undergoing surgical procedures where spinal tissues are removed as a normal part of their procedure.  Material from adults may be collected as a control group.


Exclusion Criteria:

  • Patients undergoing spinal surgery for non-degenerative spinal surgeries and surgeries were spinal tissues are not being removed.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Mohamad Bydon, M.D.

Open for enrollment

Contact information:

Neurologic Surgery Research Team

(507) 538-6546

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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