A Study to Examine Stress Management and Resilience Training (SMART) Outcomes Using Voice Analysis for Depression and Anxiety


About this study

The purpose of this study is to validate screening for depression and anxiety using the Ellipsis Health (EH) application, based on a person’s speech patterns and content.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Aged 18-70 years of age.
  • A DAHLC member or Mayo Clinic employee and commitment to an assessment consisting of questionnaires and voice samples every month as part of the 12 week SMART Program.
  • Patient with access to smartphone (iOS or Android operating systems).
  • Ability to complete sub-study questionnaire and provide voice samples.

Exclusion Criteria:

  • Patients with the following conditions are excluded from study participation:;
    • Parkinson’s Disease;
    • Cerebrovascular Accident (CVA) or head trauma with residual dysarthria;
    • CVA or head trauma within the prior 12 months;
    • Amyotrophic Lateral Sclerosis (ALS);
    • Unresolved congenital deafness;
    • Severe cognitive deficits (i.e., MMSE scores within the severe cognitive impairment range of 0-17);
    • Schizophrenia;
    • Psychosis.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Amir Lerman, M.D.

Contact us for the latest status

Contact information:

Diana Albers B.S.

(507) 255-6884


More information


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