A Study to Evaluate Exercise and Hypoxic Responses to Isovolemic Hemodilution in Rare Hemoglobin Variant Humans


About this study

The goal of this study is to determine how oxygen binding to reduced levels of hemoglobin affects the acute responses to oxygen delivery in exercising muscle in humans.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Healthy adult (> 18) men and women of all races and ethnic backgrounds.
  • Recruited from faculty and staff of the Mayo Medical Center and from Rochester, MN and surrounding communities. 

Exclusion Criteria:

  • Children under the age of 18 years old.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Shelly Roberts R.N.



More information


Publications are currently not available

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