A Study to Evaluate Immune and Hematopoietic Cell Assessment in Clonal B Cell Conditions


About this study

The purpose of this study is to evaluate the immune and hematopoietic compartments in patients with monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL) in comparison to age-matched healthy control (HC) donors.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • CLL patients who consent to provide research samples of blood, BM, lymphoid tissue, and their constituents (fresh and cryopreserved): 1827-00.
  • Healthy control, MBL, and CLL patients who consent to give paired blood, BM, and their constituents (fresh): 16-006204.
  • Healthy control BM from discarded surgical samples (fresh): 1062-00.
  • Healthy control apheresis blood cones (fresh): IRB exempt
  • Healthy control and MBL blood samples (cryopreserved): 489-04 and 09-003676.
  • As per each integrated IRB (above).

Exclusion Criteria: 

  • As per each integrated IRB (above).



Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kay Medina, Ph.D.

Contact us for the latest status

Contact information:

Cancer Center Clinical Trials Referral Office


More information


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