A Study of Mesenchymal Stem Cell (MSC) Adherence and Vessel Wall Penetration Following Intra-arterial Delivery Subsequent to Controlled Balloon Angioplasty

Overview

About this study

The purpose of this study is to determine the amount of MSCs that adhere to predetermined areas of arterial wall following balloon angioplasty vs no intervention, and to characterize the effect of intra-arterial injection of MSCs on predetermined areas of arterial wall via transcriptome analysis.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with advanced vascular disease who are destined for lower extremity amputation.

Exclusion Criteria:

  • Patients with septic shock due to lower extremity infection.
  • Patients who are unable or unwilling to sign consent.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Houssam Farres, M.D.

Open for enrollment

Contact information:

Houssam Farres M.D.

(904)953-2077

Farres.Houssam@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20461658

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