A Study of the Use of a Human Nerve Allograft in Laryngeal Reinnervation

Overview

About this study

The purpose of this study is to prove/disprove that human nerve allograft to recurrent laryngeal nerve anastomosis will restore vocal cord movement. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:  

  • Adult with a unilateral vocal fold paralysis with minimal chance for spontaneous recovery.
  • Patients with tumor invasion of the recurrent laryngeal nerve (RLN), patients with iatrogenic transection of the RLN.
  • Patient's age between 18 and 80-year-old, good general condition, negative pregnancy test in contraception for woman of child bearing age.

Exclusion Criteria: 

  • Patients with insufficient follow up, bilateral vocal fold paralysis, abnormal vocal fold mucosa.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Amy Rutt, D.O.

Contact us for the latest status

Contact information:

Mauricia Buchanan R.N.

(904)953-9455

Buchanan.Mauricia@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20461652

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