A Randomized Study Evaluating Patients Discharged with Indwelling Chest Tube and Valve


About this study

The purpose of this study is to analyze the effectiveness of antibiotics and closer monitoring on decreasing infection in patients discharging with a chest tube and valve in place.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • ≥ 18 years of age.
  • Male or Female.
  • Consultation with a thoracic surgeon.
  • Discharge from the hospital with a chest tube and valve in place.
  • Subject is able to understand the study procedures and provide informed consent.

Exclusion Criteria:

  • Pregnancy.
  • Allergy to cephalexin or clindamycin.
  • Special consideration should be taken in enrolling subjects with preexisting conditions that can be exacerbated by antibiotic use but are allowed at the discretion of the treating physician.
  • Considerations include but are not limited to:
    • C. difficile;
    • Colitis;
    • Impaired renal function;
    • Hypersensitivities to cephalosporins, penicillins, or lincomycin;
    • Hepatic impairment;
    • Anticoagulation therapy;
    • Metformin usage;
    • Probenecid usage.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

K Robert Shen, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Karlyn Pierson R.N., CCRP



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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