A Study to Understand Sex-Specific Effects of Endocrine Disruption on Physical Activity


About this study

The purpose of this study is to determine whether a history of premenopausal bilateral salpingo-oophorectomy (BSO, removal of ovaries and fallopian tubes) is associated with decreased performance on objective measures of physical activity.


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Currently be 55 years of age or older.
  • 50 participants:
    • Have a history of premenopausal bilateral salpingo-oophorectomy.
  • 50 participants:
    • Have no history of premenopausal bilateral salpingo-oophorectomy.
  • Participants for both cohorts must also be enrolled in another study on premenopausal bilateral salpingo-oophorectomy (IRB #18-008476).
  • Must be willing and able to complete all study activities.
  • Have provided written informed consent.

Exclusion Criteria:

  • They are younger than 55 years of age.
  • They are < 6 months post-chemotherapy.
  • They are < 6 months post-major surgery requiring general anesthesia.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Emma Fortune Ngufor, Ph.D.

Open for enrollment

Contact information:

Sarah Gifford CCRP



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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