A Study to Evaluate the Central Mechanisms of Sympathetic Neural Discharge


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 18-009225
    Sponsor Protocol Number: 18-009225

About this study

The purpose of this study to better understand the central mechanisms contributing to sympathetic discharge patterns in humans.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Subjects will be healthy adult men and women.
  • Subjects 18-45 years of age.
  • BMI <30 kg/m2.
  • Non-pregnant (women must have a negative pregnancy test and will be studied in the early follicular phase of their menstrual cycle to minimize any effects of reproductive hormone status which may alter data interpretation).
  • Non-smokers. 
  • Willing and able to give written informed consent.
  • Subjects will report to the CRTU after abstaining from caffeine, alcohol, and exercise for 24 hours.

Exclusion Criteria:

  • Pregnancy will result in exclusion from this study. 
  • Smokers.
  • Unable or unwilling to provide written informed consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Open for enrollment

Contact information:

Shelly Roberts R.N.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


Mayo Clinic Footer