A Study to Evaluate the Central Mechanisms of Sympathetic Neural Discharge


About this study

The purpose of this study to better understand the central mechanisms contributing to sympathetic discharge patterns in humans.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Subjects will be healthy adult men and women.
  • Subjects 18-45 years of age.
  • BMI < 30 kg/m^2.
  • Non-pregnant (women must have a negative pregnancy test prior to participation)
  • Non-smokers. 
  • Willing and able to give written informed consent.
  • Subjects will report to the CRTU after abstaining from caffeine, alcohol, and exercise for 24 hours.

Exclusion Criteria:

  • Pregnancy will result in exclusion from this study. 
  • Smokers.
  • Unable or unwilling to provide written informed consent.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

Contact information:

Shelly Roberts R.N.

(507) 255-2807


More information


Publications are currently not available

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