Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.See eligibility criteria
- Male and female patients ages > 18 years or older.
- Male and female patients with a clinical diagnosis of CTS and a CTS-6 score of > 12.43.
- Confirmatory electrodiagnostic testing indicating median neuropathy at the wrist (i.e., consistent with a clinical diagnosis of CTS) or ultrasound findings consistent with median nerve enlargement in the carpal tunnel.43-48.
- Candidate for surgical CTR based on severe and/or refractory symptoms.
- Following discussion of surgical options for CTR, the patient elects to proceed with USCTR.
- Inability to complete the informed consent process or outcome questionnaires.
- Previous carpal tunnel release or wrist surgery on the ipsilateral side.
- Previous history of complex regional pain syndrome (CRPS).
- Previous history of upper limb vascular disease (including documented thoracic outlet syndrome) or Raynaud’s phenomenon.
- Traumatic injury to the median nerve or any of its branches on the ipsilateral side.
- Contraindication to proceeding with USCTR based on diagnostic ultrasound.
- Patients who are anticoagulated with an INR >3.0.
- Carpal tunnel injection with corticosteroid within 6 weeks prior to anticipated procedure.