A Study of Clinical Outcomes of Ultrasound-guided Carpal Tunnel Release Performed in a Procedural Room Setting


About this study

The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Male and female patients ages > 18 years or older.
  • Male and female patients with a clinical diagnosis of CTS and a CTS-6 score of > 12.43.
  • Confirmatory electrodiagnostic testing indicating median neuropathy at the wrist (i.e., consistent with a clinical diagnosis of CTS) or ultrasound findings consistent with median nerve enlargement in the carpal tunnel.43-48.
  • Candidate for surgical CTR based on severe and/or refractory symptoms.
  • Following discussion of surgical options for CTR, the patient elects to proceed with USCTR.

Exclusion Criteria:

  • Inability to complete the informed consent process or outcome questionnaires.
  • Previous carpal tunnel release or wrist surgery on the ipsilateral side.
  • Previous history of complex regional pain syndrome (CRPS).
  • Previous history of upper limb vascular disease (including documented thoracic outlet syndrome) or Raynaud’s phenomenon.
  • Traumatic injury to the median nerve or any of its branches on the ipsilateral side.
  • Contraindication to proceeding with USCTR based on diagnostic ultrasound.
  • Patients who are anticoagulated with an INR >3.0.
  • Carpal tunnel injection with corticosteroid within 6 weeks prior to anticipated procedure.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Albert Lea, Minn.

Mayo Clinic principal investigator

Mark Ciota, M.D.

Contact us for the latest status

Contact information:

Russell Bergum D.O.

(507) 373-2384


More information


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