A Study to Compare VerifyNow PRU, Delta PRU, and Vasoactive Stimulated Phosphoprotein Flow Cytometry for Evaluating Clopidogrel Response Before and After Neurointerventional Procedures


About this study

The purpose of this study is to develop new antiplatelet agent monitoring protocols for neurointerventional procedures, using concepts of biologic variability, within-person variability, and individuality index to interpret laboratory tests of platelet function for this patient population.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 18 years of age or older.
  • English-speaking.
  • Scheduled for neurointerventional procedure requiring aspirin and clopidogrel therapy.

Exclusion Criteria: 

  • Less than 18 years of age.
  • Non-English speaking.
  • Already taking aspirin or clopidogrel before study enrollment (10 or less days prior to enrollment).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Brad Karon, M.D., Ph.D.

Open for enrollment

Contact information:

Kaitlin Schwartz



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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