A Study to Evaluate Whether or Not Extracellular Counts and Content Can Diagnose Alcoholic Hepatitis

Overview

About this study

The purpose of this study is to determine if extracellular (EV) counts and content can differentiate Alcoholic Hepatitis (AH) from alcoholic liver disease as well as end stage liver disease due to other causes.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:

  • Age >21 year old; both male or female.
  • MELD score 10 or higher.
  • Patients undergoing regular testing for liver disease including, but not limited to, pre-transplant evaluation, follow-up visits, in-patient testing, etc.

Exclusion Criteria: 

  • Potential subjects with organ failure (as defined by hepatic encephalopathy >stage 3; need for ventilator or vasopressor support; renal replacement therapy or creatinine >2.5).
  • Current or previous history of hepatocellular carcinoma or other malignancy.
  • MELD score <10.
  • Inability to give written informed consent.
  • Pregnant females or other at-risk population.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vijay Shah, M.D.

Open for enrollment

Contact information:

Amy Olofson R.N.

(507) 284-2638

Olofson.Amy@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20454965

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