A Study to Evaluate a Novel Technique to Diagnose Carotid Artery Stenosis


About this study

The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA), as compared to a duplex carotid ultrasound.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Outpatients age ≥ 65 years sent to the vascular laboratory for carotid duplex ultrasound examination who have one or more of the following risk factors for atherosclerotic disease:
    • Hypertension;
    • Hyperlipidemia;
    • Diabetes mellitus;
    • Known coronary artery/peripheral arterial disease;
    • Tobacco use (current or past);
    • Family history of early onset cardiovascular disease.

Exclusion Criteria: 

  • Inability to provide informed consent.
  • Prior neck surgery (carotid endarterectomy) or prior carotid artery stenting.
  • Aortic stenosis.
  • Congestive heart failure.
  • Body Mass Index (BMI) > 35.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Thanila Macedo, M.D.

Closed for enrollment

More information


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