Safety and Effectiveness of Esophageal Self Dilation for Benign Refractory Esophageal Stricture Management

Overview

About this study

The purpose of this study is to assess the clinical effectiveness of ESDT for patients with RBES defined as the number of endoscopic interventions  6 months following serial dilation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Therapy:

  • 18 years of age or older;
  • Patient who presents to the esophageal clinic with refractory benign esophageal strictures;
  • Refractory benign esophageal stricture defined as an esophageal stricture with persistent dysphagia despite undergoing 5 endoscopic dilations within a 1 year period;
  • Persistent dysphagia will be considered if patients has solid food dysphagia at least once a week.

Exclusion Criteria:

  • Patient with malignant esophageal stricture;
  • Angulated stricture which prevents safe passage of Maloney dilator in office setting;
  • Known significant esophageal motor disorder (i.e., achalasia, aperistalsis, functional obstruction, jackhammer, distal esophageal spasm)*;
  • The presence of esophageal stent;
  • Inability to learn self-dilation secondary to blindness or cognitive dysfunction;
  • Use of chronic anticoagulants.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Magnus Halland, M.D.

Open for enrollment

Contact information:

Debra Geno CCRP

(507)538-0367

Geno.Debra@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Francisco Ramirez, M.D.

Open for enrollment

Contact information:

Allon Kahn M.D.

(480)301-6990

Kahn.Allon@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20445682

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