Multi-Organ Magnetic Resonance Elastography to Monitor Treatment Response in Light Chain (AL) Amyloidosis


About this study

The purpose of this study is to perform multi-organ magnetic resonance elastography (MRE) in subjects with AL amyloidosis to determine feasibility of multi-organ MRE technique, and to perform multi-organ MRE in subjects with AL amyloidosis pre- and post-stem cell transplantation to obtain pilot data in patients who undergo stem cell transplantation for detection of changes post transplant.  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Diagnosis of AL amyloidosis with some patients possibly being scheduled for hematopoietic stem cell transplantation.

Exclusion Criteria:

  • Contraindications to MRI; namely, cardiac pacemakers or defibrillators.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Sudhakar Venkatesh, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Kathy Brown


More information


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