Esophageal Disease in Patients with Lung Disease:


About this study

The purpose of this study is to characterize esophageal function across a broad spectrum of pulmonary disease.

  • By exploring whether mortality and allograft rejection (acute and chronic) differs in patients with gastroesophageal reflux (GER) from those without GER, following lung transplantation.
  • By identifying specific patterns in the type/severity of GER (acid/non-acid, proximal/distal) and esophageal dysmotility (impaired reflux clearance, impaired bolus transit, decrease post-reflux swallow induced peristalsis) that will associate with respiratory function and symptoms; and in the transplant patients, post-transplant outcomes and chronic lung allograft dysfunction.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Exclusion Criteria:

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Kenneth DeVault, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Kenneth Devault M.D.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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