Multi-Center Prospective Validation Study of VTE Risk Prediction Tool in Trauma Patients

Overview

About this study

Almost one-half million people suffer venous thromboembolism annually in the United States, and one-third die from this disease. Massive bleeding from injury accounts for half of early deaths after trauma. This study aims to prevent the deaths and suffering associated with venous thromboembolism and bleeding by identifying the individual person at high risk of these complications in order to take preventive measures.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:  

  1. Male or female acute trauma patients who arrive and are admitted at one of the three Trauma Centers will be considered for enrollment into our study.
  2. Children will be included if appropriate consent can be obtained.
  3. Use of antiplatelet agents (i.e., clopidogrel, prasugrel, ticagrelor, and aspirin or NSAIDs) is allowed.

Exclusion Criteria:  

  1. Refusal or inability to provide informed consent (no family member available to obtain surrogate consent)/assent
  2. Therapeutic anticoagulation, to include warfarin, heparin, targeted anticoagulant (i.e., dabigatran etexilate, rivaroxaban, apixaban, edoxaban)
  3. An inherited or acquired bleeding disorder
  4. Presentation to Trauma Center >12 hours after injury
  5. Active cancer, sepsis, renal failure or burns.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Myung Park, M.D., M.S.

Open for enrollment

Contact information:

Derek Vanmeter

(507)286-9040

Vanmeter.Derek@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20438453

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