Arthroplasty in Patients with Osteogenesis Imperfecta


About this study

The purpose of the study is to determine the survivorship, clinical outcomes, and mechanisms of failure associated with total hip and knee arthroplasty in patients with osteogenesis imperfecta.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Diagnosis of osteogenesis imperfecta, previous total knee or hip arthroplasty, adult

Exclusion Criteria: 

  • No documented diagnosis of osteogenesis imperfecta

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Robert Trousdale, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Robert Trousdale M.D.


More information


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