A Study for Collecting Data on Subjects Undergoing Lower Body Negative Pressure (LBNP) to Simulate Progressive Blood Loss


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 18-002695
    NCT ID: NCT03582501
    Sponsor Protocol Number: 18-002695

About this study

The purpose of this study is for collecting data on subjects undergoing lower body negative pressure (LBNP) to simulate progressive blood loss to look at different variables associated with blood loss.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria:

  • Healthy subjects between 18-55 years of age
  • Non-obese (BMI < 30)
  • Non-smokers 
  • Free of any systemic diseases including hypertension, diabetes, coronary artery disease, neurologic disease, or any other major medical co-morbidity

Exclusion Criteria:

  • Children less than 18 years of age


Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Timothy Curry, M.D., Ph.D.

Closed for enrollment

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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