Investigating Dysregulation of the Glutamatergic System using High Frequency Oscillations (HFOs) in Glioma Related-Seizures


About this study

The purpose of this study is to examine the clinical utility of high frequency oscillations (HFOs) as an electrophysiological phenotypic surrogate of glioma-related seizures.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Age ≥ 18
  2. Patients who consented to the use of their medical records for research purposes
  3. Patients who presented to Mayo Clinic Florida with brain tumor-related epilepsy (BTRE)
  4. Patients undergoing awake craniotomy with ECoG during glioma resection


Exclusion Criteria: 

  1. Patients with BTRE who undergo resection without ECoG
  2. Patients with BTRE who undergo non-awake ECoG
  3. Patient with previous chronic extra-operative ECoG monitoring

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Anteneh Feyissa, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Anteneh Feyissa M.D.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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