A Study to Assess the Effect of Lower Hemoglobin Levels on Cardiac Functions in Patients with Cardiac Diseases


About this study

The purpose of this study is to test if a reduction of hemoglobin leads to subclinical cardiac dysfunction in patients with known cardiovascular disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria:  

  1. Adult patients (≥18 years) undergoing coronary artery bypass surgery and/or aortic valve replacement surgery and aortic arch surgery.

Exclusion Criteria: 

  1. Presence of moderate to severe valvular disease other than aortic stenosis (stenosis or regurgitation)
  2. Presence of shock (SBP <90mmHg) or requirement of vasopressors or inotropes to support cardiac output or maintain systematic blood pressure
  3. Presence of severe left ventricular dysfunction (EF <35%)
  4. Mechanical circulatory support ( intra-aortic balloon pump, left ventricular assist device, impella)
  5. Patients with hearth rhythms other than sinus rhythm
  6. Presence of inflitrative cardiomyopathies.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Hilal Olgun Kucuk, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Brandon Wiley M.D.



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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