A Study to Develop a Screening Method to Provide Early Detection of HPV-associated Oropharyngeal Squamous Cell Carcinoma (OSCC)


About this study

The purpose of this study is to develop a screening method to provide early detection of HPV-associated Oropharyngeal Squamous Cell Carcinoma (OSCC).


Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with tissue proven diagnosis of HPVOSCC will be recruited.
  • Five patients with HPV-negative SCC will be enrolled as negative controls.

Exclusion Criteria:

  • Patients with tissue proven diagnosis of HPV-negative HNSCC. 
  • Patients with other HPV-associated SCC, such as invasive cervical SCC in female patients, and/or anal SCC in either male or female patients, will be excluded.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Qihui Zhai, M.D.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Anna Harrell B.S., M.P.H., CCRP


More information


Publications are currently not available

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