A Study of Clinical and Radiologic Characteristics and Outcomes in Patients with Myelopathy Associated with Idiopathic Focal Displacement on MRI


About this study

The purpose of this study is to investigate the clinical presentation, radiological findings, surgical treatment, and the subsequent clinical course and outcomes of cases of myelopathy associated with idiopathic/cryptogenic causes of spinal cord displacement who have been evaluated at Mayo Clinic.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Please contact the study team to discuss whether or not you are eligible to participate in a study.

Inclusion Criteria:

  • Clinical evidence of myelopathy at the initial evaluation. 
  • Focal displacement of the spinal cord on imaging that is idiopathic (not due to obvious structural lesion such as adjacent tumor, spondylitic bar, etc). 

Exclusion Criteria: 

  • Alternative diagnoses of myelopathy such as demyelinating lesions (review of MRI of spine and brain to detect parenchymal lesions suggestive of multiple sclerosis and CSF data for markers of intrathecal IgG production), vascular malformation, spine or spinal cord tumors, spinal infarct, spinal infections, spondylotic myelopathy.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Brian Weinshenker, M.D.

Contact us for the latest status

Contact information:

Diana Londono M.D.

(507) 538-3761


More information


Publications are currently not available

Study Results Summary

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Supplemental Study Information

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