Study Analyzing Use of Mucosal Impedance in Evaluation of Gastroesophageal Reflux Disease


About this study

The purpose of this study is to evaluate the accuracy of balloon catheter based mucosal impedance for the diagnosis of GERD in patients who have undergone Peroral Endoscopic Myotomy (POEM).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients who are greater than 18 years old.
  • Patients who are already undergoing EGD and 48-hour wireless pH monitoring off PPI.
  • Patients who are able to provide informed consent for mucosal impedance balloon testing.

Exclusion Criteria:

  • Patients who are not eligible for EGD due to comorbidities.
  • Patients with erosive esophagitis Los Angeles C or D on endoscopy, in whom the diagnosis of GERD is not uncertain.



Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Jennifer Horsley-Silva, M.D.

Closed for enrollment

Contact information:

Jennifer Horsley-Silva M.D.

(480) 301-6990

More information


Publications are currently not available

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