A Study of a Psychotherapeutic Approach Applied to Those Who are Critically Ill to Provide Patients with Psychological Support


About this study

The objective of this project is to refine and test a behavioral intervention to be administered in parallel with medical treatment in the ICU.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults (age >18) admitted to the ICU and expected to stay >48 hours.
  • Critically ill adult patients requiring vasopressor support or mechanical ventilation.
  • Patients with respiratory distress and on BiPAP/CPAP/High flow oxygen.
  • Willing patient’s family member; critical care nurses taking care of patients receiving EPSCI.

Exclusion Criteria: 

  • History of dementia, mental retardation, suicide attempt, psychotic disorders such as schizophrenia, acute alcohol/substance intoxication or withdrawal, severe metabolic encephalopathy. 
  • Patients on comfort care. 
  • Patients not expected to survive the hospital stay or non-English speaking.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Lioudmila Karnatovskaia, M.D.

Closed for enrollment

Contact information:

Lioudmila Karnatovskaia M.D.

(904) 953-2000


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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