A Study to Assess Tissue Mechanical Properties as a Prognostic Biomarker of Breast Cancer using MR Elastography


About this study

The purpose of this study is to investigate the mechanical properties of breast tissue on MRE (including stiffness, elasticity, viscosity, and volumetric stain) to find any correlation between these variables with breast density and background parenchymal enhancement, both of which are considered independent risk factors for breast carcinoma. We can also assess any suspicious lymph nodes noted on diagnostic MRI and correlate with stiffness values of the lymph nodes on MRI.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Female patients older than 18 years.

Exclusion Criteria: 

  • Pregnant and lactating females will be excluded (we will correlate with urine test administered prior to their clinical MRI; no additional urine sample will be obtained for the elastography portion of the study).
  • Patients with implanted devices including aneurysm clips, pacemakers, coils, filters, and electronic pumps will be excluded.
  • Patients under the age of 18 will be excluded.
  • Patient without decision making capacity will be excluded.
  • Patients with breast implants will be excluded.


Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kathleen Brandt, M.D.

Closed for enrollment

Contact information:

Kathryn Stern

(507) 284-4269


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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