Effects of Social Media Use on Self-esteem, Depressive Symptoms, Psychiatric Morbidity, and Physiological Markers of Stress in Adolescent Psychiatric Patients and Healthy Controls


  • Study type

  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-004511
    Sponsor Protocol Number: 17-004511

About this study

The purpose of this study is to contribute to our understanding of the relationships between social media use in adolescents and psychological development, psychiatric comorbidity, and physiological markers of stress. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria

  • Adolescents between the ages of 13 to 17 years
  • Depressed participants will have a diagnosis of major depressive disorder based on a M.I.N.I. KID interview and a QIDS-A17-C score of 11 or higher (moderate to severe symptoms). Healthy control participants will have no psychiatric diagnosis based on a M.I.N.I KID interview and a QIDS-A17-C score of <6.
  • Enrolled in school
  • Adolescent participants must have the capacity to provide informed assent
  • Parents must have the capacity to provide informed consent
  • Willingness and ability to adhere to study procedures
  • Participant will have access to an electronic portable device (e.g. phone, tablet, laptop) with internet capabilities

Exclusion Criteria

  • Steroid based medication (e.g. corticosteroid inhalers in asthmatic)
  • Learning or language difficulties that would limit ability to understand verbal or written English instructions as could negate questionnaire results
  • Imminent suicidal intent
  • Refusal or withdrawal of consent
  • Inability or unwillingness to adhere to study procedures

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Paul Croarkin, D.O., M.S.

Open for enrollment

Contact information:

Reem Shafi M.B.B.S.



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


Mayo Clinic Footer