Assessment of the QT Interval Using a Smartphone ECG Device during Antiarrhythmic Drug Initiation


About this study

  1. Obtain AliveCor ECG Recordings from subjects at the time of clinically indicated ECGs over the course their anti-arrhythmic drug loading hospital admission. 
  2. Create and refine an AliveCor algorithm to accurately measure a patient’s QT interval and heart rate corrected QTc value and validate/compare the results against the 12- lead ECGs on record.
  3. Obtain AliveCor ECG recordings at the time of daily clinically indicated electrolyte panels to further develop and refine a Potassium screening algorithm.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients 18 and older  
  • Admitted to the hospital for initiation of dofetilide or sotalol on the basis of routine electrophysiologic care (no patients will specifically receive dofetilide or sotalol because of their participation in this research study). 

Exclusion Criteria:

  • Patients  <18 years of age
  • Patients admitted for dose adjustments, or following non-standard dosing protocols, will be excluded
  • Patients without the ability to understand and sign a written informed consent form, which must be obtained prior to initiation of study

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Peter Noseworthy, M.D.

Open for enrollment

Contact information:

Trena Thome

More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


Mayo Clinic Footer