CTA Perforator Localization for Virtual Surgical Planning of Osteocutaneous Fibular Free Flaps in Head and Neck Reconstruction


About this study

The purpose of this study is to prospectively investigate the accuracy and reliability of the computed tomographic angiography (CTA) perforator tracing method across two high volume tertiary care institutions currently utilizing virtual surgical planning (VSP) for osteocutaneous fibular free flap reconstructions (Mayo Clinic Rochester / University of Florida-Jacksonville).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Osteocutaneous fibular free flap reconstruction being performed for a head and neck reconstructive defect 
  • Adequate clinical documentation of intraoperative perforator locations and need for intraoperative modification of virtual surgical plan within retrospectively identified patients 
  • A minimum postoperative follow up of 30 days to assess for flap related complications and outcomes

Exclusion Criteria:

  • Preoperative imaging modality other than CTA utilized to verify lower extremity three vessel run-off 
  • Head and neck defects not necessitating composite reconstruction with bone and a soft tissue skin paddle 
  • Lack of patient three vessel run-off in the lower extremity precluding use of fibular free flap reconstruction 
  • Inadequate clinical documentation of intraoperative perforator locations for retrospectively identified patients 
  • Inadequate documentation of need to modify intraoperative virtual surgical plan for retrospectively identified patients 
  • Less than 30 days of postoperative follow up to assess flap related outcomes.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Kevin Arce Castro, M.D., D.M.D.

Contact us for the latest status

Contact information:

Kevin Arce Castro M.D., D.M.D.

(507) 538-1943


More information


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Study Results Summary

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Supplemental Study Information

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