A Study to Gather Information to Develop and Validate a Tool for Predicting the Response to Cardiac Resynchronization (CRT) Therapy


About this study

The purpose of this study is to gather information to develop and validate a predictive tool for predicting the response to CRT therapy.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Adults patients 18 years and older.
  • Patients who are recommended to receive a CRT device for HF according to current AHA/ACC/HRS guideline (LVEF≤35%, NYHA class II-IV, QRS≥120ms, LBBB).
  • English speaking.
  •  Able to provide informed consent.

Exclusion Criteria:

  • Not English speaking.
  • Not able to provide informed consent.
  • Advanced comorbid conditions with life expectancy <1 year.
  • Patient is <18 of years of age.
  • Patient has a CRT-P or CRT-D device.
  • Patient who are recommended but unable to receive a CRT device.
  • Unwilling or unable to return for follow-up blood draws.



Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Yongmei Cha, M.D.

Closed for enrollment

Contact information:

Yongmei Cha M.D.

(507) 255-7369


More information


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