A Study of Normative Data for Bone-conducted VEMP Responses (amplitude, latency, threshold, asymmetry, signal-to-noise ratio) in Patients Without Vestibular Dysfunction

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-008506
    Sponsor Protocol Number: 17-008506

About this study

The purpose of this study is to develop a set of normative data for bone-conducted VEMP responses (amplitude, latency, threshold, asymmetry, signal-to-noise ratio) in patients without vestibular dysfunction, and to assess the reliability and replicability of these responses.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

Inclusion Criteria: 

  • Adult or children subjects with present and symmetrical cervical and ocular VEMPs elicited with air-conduction stimuli.  Subjects will not be excluded due to additional otologic presentation (e.g., hearing loss, tinnitus).
  • Patients who have undergone a unilateral cochlear implantation and device activation referred by our Cochlear Implant Clinic.
  • Typically-developing children without balance disorders will serve as participants for this investigation. 

Exclusion Criteria: 

  • Patients less than 6 years of age. 
  • Subjects will be excluded if they are unable to maintain muscle contraction sufficient to record responses.
  • Patients with significant orthopedic and/or neurological deficits that influence balance or mobility performance, and prevent reliable completion of the testing procedures will be excluded from the study.
  • Additional handicap that would limit the patient from being able to follow study instructions.

 

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Devin McCaslin, Ph.D.

Open for enrollment

Contact information:

Paula Orr CCRP

7741231

Orr.Paula@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20385845

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