Imaging Response to Immunotherapy and Radiation Therapy in Patients With Liver Metastases


About this study

Patients will be imaged with MRE at the time of the RT planning MRI, prior to the induction of RT and immunotherapy. Research imaging will be in addition to standard imaging studies performed at time points consistent with the standard of care (at the time of the RT planning MRI and the first clinical follow-up). An additional MRE exam will be performed at the end of treatment outside the standard of care imaging.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years
  • Diagnosis of solid cancers with the presence of one or more liver metastases
  • Minimum metastasis diameter ≥ 2 cm
  • Planning to receive radiation therapy with immunotherapy
  • Willingness to participate in mandatory imaging studies at Mayo Clinic Rochester

Exclusion Criteria:

  • Contraindications for MRI including claustrophobia, pace maker, metal implants, aneurism clips
  • Patients who are not able to consent

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Sean Park, M.D., Ph.D.

Closed for enrollment

More information


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