A Study to Collect Maternal Blood Samples to Isolate DNA for Prenatal Screening (NIPS) in Patients Undergoing Prenatal Chromosomal Testing


About this study

The purpose of this study is to collect maternal peripheral blood samples to isolate cell-free DNA to be used for non-invasive prenatal screening (NIPS) in patients undergoing diagnostic prenatal chromosomal microarray testing on chorionic villi or amniotic fluid samples, thereby having a diagnostic result to correlate with the screening result from NIPS.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Women undergoing CVS or amniocentesis for genomic testing (chromosomal microarray, test CMAP)

Exclusion Criteria: 

  • Pregnant patients under age 18

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Nicole Thorland, Ph.D.

Closed for enrollment

More information


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