Lidocaine as an Endotracheal Tube (ETT) Cuff Media


About this study

Researchers will compare the effects of lidocaine versus air, as a way to fill the breathing tube cuff which is gently inflated to hold in place the trachea (airway) during surgery. Air is the traditional method used to inflate the breathing tube cuff. Researchers wish to find if lidocaine works better than air to facilitate tolerance to the breathing tube (decreased coughing, sore throat, hoarseness). They also want to learn more about its effectiveness for this particular surgical intervention.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Patients who meet the inclusion criteria below and are expected to require ventilatory support for a period of less than 5 hours post-operatively in the cardiac ICU will be enrolled.

  • All patients > 18 years of age (male and female) who will receive general anesthesia for cardiac surgery at St. Mary’s Hospital (SMH) in Rochester, MN
  • Cardiac surgery includes: single valve repair, myectomy, CABG, pericardectomy.
  • Patients who are anticipatedto be deemed, “rapid recovery,”in the cardiac surgery ICU at St. Mary’s Hospital

Exclusion Criteria:

  • Age < 18 years old at time of surgery
  • Patients who cannot consent themselves or non-English speaking patients who require an interpreter
  • Patients who are not sent to the cardiac ICU post-operatively
  • Patients who are anticipated to have a difficult tracheal intubation
  • Patients having risk factors of postoperative aspiration of gastric contents
  • Patients who have respiratory disease or recent respiratory tract infection
  • > 2 attempts to secure an airway
  • Patients undergoing TAVR procedures or any form of “robotic,” procedures

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Troy Seelhammer, M.D.

Closed for enrollment

Contact information:

Eric DuBois R.N.


More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

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