Gastrointestinal Lewy Bodies: A Cause or Effect of Parkinson’s Disease?

Overview

About this study

The purpose of this proposal is to explore whether the presence of Lewy pathology in the gastrointestinal tract is associated with functional disturbances such as constipation and dysphagia in both Parkinson’s disease patients and non-Parkinson’s disease patients, and if present in the latter patients whether this relates to the subsequent development of Parkinson’s disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:   

  • Age 18 years or older
  • Able to provide informed consent
  • Resident of the United States (to make it possible to conduct future subject follow-up using the National Death Index)
  • Undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation

Exclusion Criteria:

  • Patients not undergoing colonoscopy and/or esophagogastroscopy and/or surgery as part of routine clinical investigation
  • Patients with bleeding disorder

 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Jacksonville, Fla.

Mayo Clinic principal investigator

Kenneth DeVault, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20359591

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