Intra and Inter-subject Reliability of Near-infrared Spectroscopy (NIRS) During Exercise


About this study

The purpose of this study is to determine if the near-infrared spectroscopy  (NIRS) and electromyography (EMG) signal during isometric handgrip exercise is reproducible within subjects (for the same and different limbs) and between subjects.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • 18-40 years old 
  • BMI 18-30 kg m²

Exclusion Criteria: 

  • Musculoskeletal injury to either forearm or wrist, any significant metabolic, cardiovascular, neurological or respiratory ailments

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Michael Joyner, M.D.

Closed for enrollment

More information


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