A Study of Assessment of Affect, Behavior, and Cognition in Children Undergoing General Anesthesia


About this study

The overall objective of this study is to develop the tools and preliminary data to permit the evaluation of the proposed conceptual framework of how procedures requiring anesthesia affect child health. 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Parents of children who are scheduled to receive general anesthesia for elective procedures more than 1 week from the date of review will be contacted by study personnel for recruitment and written informed consent obtained. 
  • Age 2.5 to 6 at date of recruitment.
  • Scheduled to receive general anesthesia for non-cardiac procedures.
  • Reside within 50 miles of the city of Rochester.

Exclusion Criteria:  

  • Preexisting diagnosis of severe developmental delay or neurological impairments.
  • Procedures that may significantly affect the function of brain such as brain resection or radiation. 
  • Anticipated hospitalization > 1 week.
  • Children who have injury or surgery to hands that make fine motor testing impossible.
  • Children whose parents do not speak English.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Yu Shi, M.D., M.P.H.

Closed-enrolling by invitation

What is this? (?)
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Kelly Haines R.R.T., L.R.T.



More information


Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available


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