Characterizing the Inflammatory Marker Profiles of Free Flap Reconstructive Head and Neck Surgery


About this study

The purpose of this study is to characterize the inflammatory markers of free flap reconstructive head and neck surgery in humans by analyzing specific inflammatory markers in blood samples from patients with the hope of better understanding free flap physiology in order to eventually improve patient outcomes.  

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patient is between ages 18 and 65
  • Must be undergoing reconstructive head and neck surgery following cancer excision
  • Patient must be undergoing either a radial forearm free flap, fibular free flap, or scapular system free flap performed by the Otolaryngology-Head and Neck Surgery (Mayo Clinic, RST) department.

Exclusion Criteria

  • Anyone who is currently taking immunomodulatory or immunosuppressant medications
  • Anyone with a history of autoimmune disease
  • Anyone with a current diagnosis of type II diabetes mellitus or chronic kidney disease
  • Anyone who is pregnant

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Jeffrey Janus, M.D.

Closed for enrollment

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