Comparison of CMC Arthrodesis and Ligament Reconstruction and Tendon Interposition in the Treatment of Basal Thumb Arthritis


About this study

The purpose of this study is to compare the techniques of ligament reconstruction tendon interposition (LRTI) and arthrodesis for the treatment of trapezio-metacarpal (TMC) joint arthritis in terms of patients’ satisfaction, pain reduction, strength, motion and radiographic outcomes.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Ligament reconstruction with tendon interposition
  • Trapezio-metacarpal fusion

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Marco Rizzo, M.D.

Closed for enrollment

More information


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