A Prevalence and Incidence Study Burden of Atrial and Ventricular Arrhythmias in Patients with Sleep Apnea and Hypertrophic Cardiomyopathy

Overview

  • Study type

    Observational
  • Study IDs

  • Describes the nature of a clinical study. Types include:

    • Observational study — observes people and measures outcomes without affecting results.
    • Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
    • Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
  • Site IRB
    • Rochester, Minnesota: 17-003514
    Sponsor Protocol Number: 17-003514

About this study

The purpose of this study is to determine prevalence of sleep apnea in patients with hypertrophic cardiomyopathy and the risk of atrial and ventricular arrhythmias.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. If you need assistance understanding the eligibility criteria, please contact the study team.

See eligibility criteria

Inclusion Criteria:

  • Adults age > 18 years old.
  • Adults with a diagnosis of HCM.
  • Both sexes.
  • Able to consent.
  • Non-pregnant.
  • Healthy controls free of hypertrophic cardiomyopathy and without a definitive family history of hypertrophic cardiomyopathy.

Exclusion Criteria:

  • Decompensated heart failure at time of enrollment (prior history of HF is not an exclusion criteria).
  • Current smokers or recently quit (< 6 months).
  • Severe (known) COPD (FEV1 between 30 and 50 percent of normal).
  • Known autonomic dysfunction.
  • Vulnerable study populations except for minorities (minorities may be targeted to achieve 25% minority recruitment required by the NIH).
  • Pregnant women.
  • Children.
  • For Aim 3b only: prior catheter ablation for atrial fibrillation.

Participating Mayo Clinic locations

Study statuses change often. Please contact us for help.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Virend Somers, M.D., Ph.D.

Open for enrollment

Contact information:

Hannah Frost

(507)293-2762

mailto:CPLHCM@mayo.edu

More information

Publications

Publications are currently not available

Study Results Summary

Not yet available

Supplemental Study Information

Not yet available

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CLS-20323064

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